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Structural and Functional Insight Into the Glycosylation Impact Upon the HGF/c-Met Signaling Pathway
Upon interactions with its specific ligand hepatocyte growth factor (HGF), the c-Met signal is relayed to series of downstream pathways, exerting essential biological roles. Dysregulation of the HGF-c-Met signaling pathway has been implicated in the onset, progression and metastasis of various cance...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2020-06-01
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| 叢編: | Frontiers in Cell and Developmental Biology |
| 主題: | |
| 在線閱讀: | https://www.frontiersin.org/article/10.3389/fcell.2020.00490/full |
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