Chimpanzee Fab Fragments and a Derived Humanized Immunoglobulin G1 Antibody That Efficiently Cross-Neutralize Dengue Type 1 and Type 2 Viruses

Passive immunization with monoclonal antibodies from humans or nonhuman primates represents an attractive alternative to vaccines for prevention of illness caused by dengue viruses (DENV) and other flaviviruses, including the West Nile virus. In a previous study, repertoire cloning to recover Fab fr...

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Bibliografiske detaljer
Main Authors: Goncalvez, Ana P., Men, Ruhe, Wernly, Claire, Purcell, Robert H., Lai, Ching-Juh
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC525007/
https://ncbi.nlm.nih.gov/pubmed/15542643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.23.12910-12918.2004
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