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Chimpanzee Fab Fragments and a Derived Humanized Immunoglobulin G1 Antibody That Efficiently Cross-Neutralize Dengue Type 1 and Type 2 Viruses

Passive immunization with monoclonal antibodies from humans or nonhuman primates represents an attractive alternative to vaccines for prevention of illness caused by dengue viruses (DENV) and other flaviviruses, including the West Nile virus. In a previous study, repertoire cloning to recover Fab fr...

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Detalles Bibliográficos
Main Authors: Goncalvez, Ana P., Men, Ruhe, Wernly, Claire, Purcell, Robert H., Lai, Ching-Juh
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC525007/
https://ncbi.nlm.nih.gov/pubmed/15542643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.23.12910-12918.2004
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