Genetic Determinants Responsible for Acquisition of Dengue Type 2 Virus Mouse Neurovirulence

Studies conducted some 50 years ago showed that serial intracerebral passage of dengue viruses in mice selected for neurovirulent mutants that also exhibited significant attenuation for humans. We investigated the genetic basis of mouse neurovirulence of dengue virus because it might be directly or...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Bray, Michael, Men, Ruhe, Tokimatsu, Issei, Lai, Ching-Juh
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Viral Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124649/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9445071/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.2.1647-1651.1998
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