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Genetic Determinants Responsible for Acquisition of Dengue Type 2 Virus Mouse Neurovirulence

Studies conducted some 50 years ago showed that serial intracerebral passage of dengue viruses in mice selected for neurovirulent mutants that also exhibited significant attenuation for humans. We investigated the genetic basis of mouse neurovirulence of dengue virus because it might be directly or...

詳細記述

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書誌詳細
主要な著者: Bray, Michael, Men, Ruhe, Tokimatsu, Issei, Lai, Ching-Juh
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 1998
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC124649/
https://ncbi.nlm.nih.gov/pubmed/9445071
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