Identification by Phage Display and Characterization of Two Neutralizing Chimpanzee Monoclonal Antibodies to the Hepatitis E Virus Capsid Protein

Two monoclonal antibodies (MAbs) against the ORF2 protein of the SAR-55 strain of hepatitis E virus (HEV) were isolated by phage display from a cDNA library of chimpanzee (Pan troglodytes) γ1/κ antibody genes. Both MAbs, HEV#4 and HEV#31, bound to reduced, denatured open reading frame 2 (ORF2) prote...

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Main Authors: Schofield, D. J., Glamann, J., Emerson, S. U., Purcell, R. H.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2000
נושאים:
Pathogenesis and Immunity
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC112041/
https://ncbi.nlm.nih.gov/pubmed/10823861
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