Identification by Phage Display and Characterization of Two Neutralizing Chimpanzee Monoclonal Antibodies to the Hepatitis E Virus Capsid Protein

Two monoclonal antibodies (MAbs) against the ORF2 protein of the SAR-55 strain of hepatitis E virus (HEV) were isolated by phage display from a cDNA library of chimpanzee (Pan troglodytes) γ1/κ antibody genes. Both MAbs, HEV#4 and HEV#31, bound to reduced, denatured open reading frame 2 (ORF2) prote...

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Vydáno v:	J Virol
Hlavní autoři:	Schofield, D. J., Glamann, J., Emerson, S. U., Purcell, R. H.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2000
Témata:	Pathogenesis and Immunity
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112041/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10823861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.12.5548-5555.2000
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