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Identification of Epithelial Phospholipase A(2) Receptor 1 as a Potential Target in Asthma

Secreted phospholipase A(2)s (sPLA(2)s) regulate eicosanoid formation and have been implicated in asthma. Although sPLA(2)s function as enzymes, some of the sPLA(2)s bind with high affinity to a C-type lectin receptor, called PLA2R1, which has functions in both cellular signaling and clearance of sP...

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Bibliografiska uppgifter
I publikationen:Am J Respir Cell Mol Biol
Huvudupphovsmän: Nolin, James D., Ogden, H. Luke, Lai, Ying, Altemeier, William A., Frevert, Charles W., Bollinger, James G., Naika, Gajendra S., Kicic, Anthony, Stick, Stephen M., Lambeau, Gerard, Henderson, William R., Gelb, Michael H., Hallstrand, Teal S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Thoracic Society 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248949/
https://ncbi.nlm.nih.gov/pubmed/27448109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0150OC
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