Identification of Epithelial Phospholipase A(2) Receptor 1 as a Potential Target in Asthma

Secreted phospholipase A(2)s (sPLA(2)s) regulate eicosanoid formation and have been implicated in asthma. Although sPLA(2)s function as enzymes, some of the sPLA(2)s bind with high affinity to a C-type lectin receptor, called PLA2R1, which has functions in both cellular signaling and clearance of sP...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Respir Cell Mol Biol
Prif Awduron: Nolin, James D., Ogden, H. Luke, Lai, Ying, Altemeier, William A., Frevert, Charles W., Bollinger, James G., Naika, Gajendra S., Kicic, Anthony, Stick, Stephen M., Lambeau, Gerard, Henderson, William R., Gelb, Michael H., Hallstrand, Teal S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2016
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248949/
https://ncbi.nlm.nih.gov/pubmed/27448109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0150OC
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