Identification of Epithelial Phospholipase A(2) Receptor 1 as a Potential Target in Asthma

Secreted phospholipase A(2)s (sPLA(2)s) regulate eicosanoid formation and have been implicated in asthma. Although sPLA(2)s function as enzymes, some of the sPLA(2)s bind with high affinity to a C-type lectin receptor, called PLA2R1, which has functions in both cellular signaling and clearance of sP...

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Enregistré dans:
Détails bibliographiques
Publié dans:Am J Respir Cell Mol Biol
Auteurs principaux: Nolin, James D., Ogden, H. Luke, Lai, Ying, Altemeier, William A., Frevert, Charles W., Bollinger, James G., Naika, Gajendra S., Kicic, Anthony, Stick, Stephen M., Lambeau, Gerard, Henderson, William R., Gelb, Michael H., Hallstrand, Teal S.
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2016
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248949/
https://ncbi.nlm.nih.gov/pubmed/27448109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0150OC
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