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Identification of Epithelial Phospholipase A(2) Receptor 1 as a Potential Target in Asthma
Secreted phospholipase A(2)s (sPLA(2)s) regulate eicosanoid formation and have been implicated in asthma. Although sPLA(2)s function as enzymes, some of the sPLA(2)s bind with high affinity to a C-type lectin receptor, called PLA2R1, which has functions in both cellular signaling and clearance of sP...
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| Publicat a: | Am J Respir Cell Mol Biol |
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| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Thoracic Society
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5248949/ https://ncbi.nlm.nih.gov/pubmed/27448109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0150OC |
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