Identification of Epithelial Phospholipase A(2) Receptor 1 as a Potential Target in Asthma

Secreted phospholipase A(2)s (sPLA(2)s) regulate eicosanoid formation and have been implicated in asthma. Although sPLA(2)s function as enzymes, some of the sPLA(2)s bind with high affinity to a C-type lectin receptor, called PLA2R1, which has functions in both cellular signaling and clearance of sP...

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Detalles Bibliográficos
Publicado en:Am J Respir Cell Mol Biol
Main Authors: Nolin, James D., Ogden, H. Luke, Lai, Ying, Altemeier, William A., Frevert, Charles W., Bollinger, James G., Naika, Gajendra S., Kicic, Anthony, Stick, Stephen M., Lambeau, Gerard, Henderson, William R., Gelb, Michael H., Hallstrand, Teal S.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2016
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248949/
https://ncbi.nlm.nih.gov/pubmed/27448109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0150OC
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