Secreted phospholipase A(2) group X acts as an adjuvant for type-2 inflammation leading to an allergen-specific immune response in the lung

Secreted phospholipase A(2) (sPLA(2)) enzymes release free fatty acids, including arachidonic acid and generate lysophosphospholipds from phospholipids, including membrane phospholipids from cells and bacteria and surfactant phospholipids. We have shown that an endogenous enzyme sPLA(2) group X (sPL...

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Pubblicato in:J Immunol
Autori principali: Ogden, Herbert Luke, Lai, Ying, Nolin, James D., An, Dowon, Frevert, Charles W., Gelb, Michael H., Altemeier, William A., Hallstrand, Teal S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375513/
https://ncbi.nlm.nih.gov/pubmed/32341057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000102
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