Secreted PLA(2) group X orchestrates innate and adaptive immune responses to inhaled allergen

Phospholipase A(2) (PLA(2)) enzymes regulate the formation of eicosanoids and lysophospholipids that contribute to allergic airway inflammation. Secreted PLA(2) group X (sPLA(2)-X) was recently found to be increased in the airways of asthmatics and is highly expressed in airway epithelial cells and...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Nolin, James D., Lai, Ying, Ogden, Herbert Luke, Manicone, Anne M., Murphy, Ryan C., An, Dowon, Frevert, Charles W., Ghomashchi, Farideh, Naika, Gajendra S., Gelb, Michael H., Gauvreau, Gail M., Piliponsky, Adrian M., Altemeier, William A., Hallstrand, Teal S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752296/
https://ncbi.nlm.nih.gov/pubmed/29093264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94929
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