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Lipids modulate the conformational dynamics of a secondary multidrug transporter

Direct interactions with lipids have emerged as key determinants of the folding, structure and function of membrane proteins, but an understanding of how lipids modulate protein dynamics is still lacking. Here, we systematically explored the effects of lipids on the conformational dynamics of the pr...

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Dettagli Bibliografici
Pubblicato in:Nat Struct Mol Biol
Autori principali: Martens, Chloé, Stein, Richard A, Masureel, Matthieu, Roth, Aurélie, Mishra, Smriti, Dawaliby, Rosie, Konijnenberg, Albert, Sobott, Frank, Govaerts, Cédric, Mchaourab, Hassane S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248563/
https://ncbi.nlm.nih.gov/pubmed/27399258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3262
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