PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome

The emergence of avian H7N9 influenza A virus in humans with associated high mortality has highlighted the threat of a potential pandemic. Fatal H7N9 infections are characterized by hyperinflammation and increased cellular infiltrates in the lung. Currently there are limited therapies to address the...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Pinar, Anita, Dowling, Jennifer K., Bitto, Natalie J., Robertson, Avril A. B., Latz, Eicke, Stewart, Cameron R., Drummond, Grant R., Cooper, Matthew A., McAuley, Julie L., Tate, Michelle D., Mansell, Ashley
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247656/
https://ncbi.nlm.nih.gov/pubmed/27913620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.756379
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