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Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition
The inflammasome NLRP3 is activated by pathogen associated molecular patterns (PAMPs) during infection, including RNA and proteins from influenza A virus (IAV). However, chronic activation by danger associated molecular patterns (DAMPs) can be deleterious to the host. We show that blocking NLRP3 act...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4901306/ https://ncbi.nlm.nih.gov/pubmed/27283237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27912 |
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