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Novel Insights into the Physiological Function of the APP (Gene) Family and Its Proteolytic Fragments in Synaptic Plasticity

The amyloid precursor protein (APP) is well known to be involved in the pathophysiology of Alzheimer's disease (AD) via its cleavage product amyloid ß (Aß). However, the physiological role of APP, its various proteolytic products and the amyloid precursor-like proteins 1 and 2 (APLP1/2) are sti...

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Détails bibliographiques
Publié dans:Front Mol Neurosci
Auteurs principaux: Ludewig, Susann, Korte, Martin
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247455/
https://ncbi.nlm.nih.gov/pubmed/28163673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00161
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