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Novel Insights into the Physiological Function of the APP (Gene) Family and Its Proteolytic Fragments in Synaptic Plasticity

The amyloid precursor protein (APP) is well known to be involved in the pathophysiology of Alzheimer's disease (AD) via its cleavage product amyloid ß (Aß). However, the physiological role of APP, its various proteolytic products and the amyloid precursor-like proteins 1 and 2 (APLP1/2) are sti...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Ludewig, Susann, Korte, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247455/
https://ncbi.nlm.nih.gov/pubmed/28163673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00161
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