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Novel Insights into the Physiological Function of the APP (Gene) Family and Its Proteolytic Fragments in Synaptic Plasticity

The amyloid precursor protein (APP) is well known to be involved in the pathophysiology of Alzheimer's disease (AD) via its cleavage product amyloid ß (Aß). However, the physiological role of APP, its various proteolytic products and the amyloid precursor-like proteins 1 and 2 (APLP1/2) are sti...

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Publicat a:Front Mol Neurosci
Autors principals: Ludewig, Susann, Korte, Martin
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247455/
https://ncbi.nlm.nih.gov/pubmed/28163673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00161
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