Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: Influence of osteotropic factors

BACKGROUND: Osteoarthritis (OA) is the most common human joint disease. Recent studies suggest that an abnormal subchondral bone metabolism is intimately involved in the genesis of this disease. Bone remodelling is tightly regulated by a molecular triad composed of OPG/RANK/RANKL. RANKL exists as 3...

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發表在:Bone
Main Authors: Tat, Steeve Kwan, Pelletier, Jean-Pierre, Lajeunesse, Daniel, Fahmi, Hassan, Duval, Nicolas, Martel-Pelletier, Johanne
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247263/
https://ncbi.nlm.nih.gov/pubmed/18539107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2008.04.006
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