Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts

INTRODUCTION: In osteoarthritis (OA), the subchondral bone undergoes a remodelling process involving several factors synthesized by osteoblasts. In this study, we investigated the expression, production, modulation, and role of PAR-2 in human OA subchondral bone osteoblasts. MATERIALS AND METHODS: P...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Amiable, Nathalie, Tat, Steeve Kwan, Lajeunesse, Daniel, Duval, Nicolas, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Boileau, Christelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250314/
https://ncbi.nlm.nih.gov/pubmed/19264156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2009.02.015
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