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Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: Influence of osteotropic factors

BACKGROUND: Osteoarthritis (OA) is the most common human joint disease. Recent studies suggest that an abnormal subchondral bone metabolism is intimately involved in the genesis of this disease. Bone remodelling is tightly regulated by a molecular triad composed of OPG/RANK/RANKL. RANKL exists as 3...

詳細記述

保存先:
書誌詳細
出版年:Bone
主要な著者: Tat, Steeve Kwan, Pelletier, Jean-Pierre, Lajeunesse, Daniel, Fahmi, Hassan, Duval, Nicolas, Martel-Pelletier, Johanne
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247263/
https://ncbi.nlm.nih.gov/pubmed/18539107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2008.04.006
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