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Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: Influence of osteotropic factors

BACKGROUND: Osteoarthritis (OA) is the most common human joint disease. Recent studies suggest that an abnormal subchondral bone metabolism is intimately involved in the genesis of this disease. Bone remodelling is tightly regulated by a molecular triad composed of OPG/RANK/RANKL. RANKL exists as 3...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Tat, Steeve Kwan, Pelletier, Jean-Pierre, Lajeunesse, Daniel, Fahmi, Hassan, Duval, Nicolas, Martel-Pelletier, Johanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247263/
https://ncbi.nlm.nih.gov/pubmed/18539107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2008.04.006
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