Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: Influence of osteotropic factors

BACKGROUND: Osteoarthritis (OA) is the most common human joint disease. Recent studies suggest that an abnormal subchondral bone metabolism is intimately involved in the genesis of this disease. Bone remodelling is tightly regulated by a molecular triad composed of OPG/RANK/RANKL. RANKL exists as 3...

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Enregistré dans:
Détails bibliographiques
Publié dans:Bone
Auteurs principaux: Tat, Steeve Kwan, Pelletier, Jean-Pierre, Lajeunesse, Daniel, Fahmi, Hassan, Duval, Nicolas, Martel-Pelletier, Johanne
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247263/
https://ncbi.nlm.nih.gov/pubmed/18539107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2008.04.006
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