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The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor κB ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an indicator of the metabolic state of these disease cells

OBJECTIVE: We previously reported that human OA subchondral bone osteoblasts could be discriminated into two subpopulations identified by their levels of endogenous production (low [L] or high [H]) of PGE(2). Here, we investigated the OPG and RANKL expression levels, the histologic analysis of the s...

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Bibliografske podrobnosti
izdano v:Clin Exp Rheumatol
Main Authors: Tat, Steeve Kwan, Pelletier, Jean-Pierre, Lajeunesse, Daniel, Fahmi, Hassan, Lavigne, Martin, Martel-Pelletier, Johanne
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247261/
https://ncbi.nlm.nih.gov/pubmed/18565252
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