The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor κB ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an indicator of the metabolic state of these disease cells

OBJECTIVE: We previously reported that human OA subchondral bone osteoblasts could be discriminated into two subpopulations identified by their levels of endogenous production (low [L] or high [H]) of PGE(2). Here, we investigated the OPG and RANKL expression levels, the histologic analysis of the s...

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Опубликовано в: :Clin Exp Rheumatol
Главные авторы: Tat, Steeve Kwan, Pelletier, Jean-Pierre, Lajeunesse, Daniel, Fahmi, Hassan, Lavigne, Martin, Martel-Pelletier, Johanne
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247261/
https://ncbi.nlm.nih.gov/pubmed/18565252
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