Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development

Vascular development depends on the highly coordinated actions of a variety of angiogenic regulators, most of which apparently act downstream of vascular endothelial growth factor (VEGF). One potential such regulator is delta-like 4 ligand (Dll4), a recently identified partner for the Notch receptor...

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Detaylı Bibliyografya
Asıl Yazarlar: Gale, Nicholas W., Dominguez, Melissa G., Noguera, Irene, Pan, Li, Hughes, Virginia, Valenzuela, David M., Murphy, Andrew J., Adams, Niels C., Lin, Hsin Chieh, Holash, Jocelyn, Thurston, Gavin, Yancopoulos, George D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2004
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC524697/
https://ncbi.nlm.nih.gov/pubmed/15520367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407290101
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