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Excessive tumor-elaborated VEGF and its neutralization define a lethal paraneoplastic syndrome

Vascular endothelial growth factor (VEGF) is a potent endothelial cell mitogen and key regulator of both physiologic and pathologic (e.g., tumor) angiogenesis. In the course of studies designed to assess the ability of constitutive VEGF to block tumor regression in an inducible RAS melanoma model, m...

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Detaylı Bibliyografya
Asıl Yazarlar: Wong, Alex K., Alfert, Myra, Castrillon, Diego H., Shen, Qiong, Holash, Jocelyn, Yancopoulos, George D., Chin, Lynda
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2001
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC34694/
https://ncbi.nlm.nih.gov/pubmed/11404464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121192298
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