VEGF-Trap: A VEGF blocker with potent antitumor effects

Vascular endothelial growth factor (VEGF) plays a critical role during normal embryonic angiogenesis and also in the pathological angiogenesis that occurs in a number of diseases, including cancer. Initial attempts to block VEGF by using a humanized monoclonal antibody are beginning to show promise...

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Detalles Bibliográficos
Main Authors: Holash, Jocelyn, Davis, Sam, Papadopoulos, Nick, Croll, Susan D., Ho, Lillian, Russell, Michelle, Boland, Patricia, Leidich, Ray, Hylton, Donna, Burova, Elena, Ioffe, Ella, Huang, Tammy, Radziejewski, Czeslaw, Bailey, Kevin, Fandl, James P., Daly, Tom, Wiegand, Stanley J., Yancopoulos, George D., Rudge, John S.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC123267/
https://ncbi.nlm.nih.gov/pubmed/12177445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172398299
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