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Excessive tumor-elaborated VEGF and its neutralization define a lethal paraneoplastic syndrome

Vascular endothelial growth factor (VEGF) is a potent endothelial cell mitogen and key regulator of both physiologic and pathologic (e.g., tumor) angiogenesis. In the course of studies designed to assess the ability of constitutive VEGF to block tumor regression in an inducible RAS melanoma model, m...

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Detalhes bibliográficos
Main Authors: Wong, Alex K., Alfert, Myra, Castrillon, Diego H., Shen, Qiong, Holash, Jocelyn, Yancopoulos, George D., Chin, Lynda
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC34694/
https://ncbi.nlm.nih.gov/pubmed/11404464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121192298
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