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Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting

Genetic deletion studies have shown that haploinsufficiency of Delta-like ligand (Dll) 4, a transmembrane ligand for the Notch family of receptors, results in major vascular defects and embryonic lethality. To better define the role of Dll4 during vascular growth and differentiation, we selected the...

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Détails bibliographiques
Auteurs principaux: Lobov, I. B., Renard, R. A., Papadopoulos, N., Gale, N. W., Thurston, G., Yancopoulos, G. D., Wiegand, S. J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805530/
https://ncbi.nlm.nih.gov/pubmed/17296940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611206104
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