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Differential regulation of histone acetylation and generation of mutations in switch regions is associated with Ig class switching

Class switch recombination (CSR) allows B cells to make effective protective antibodies. CSR involves the replacement of the μ constant region with one of the downstream constant regions by recombination between the donor and recipient switch (S) regions. Although histone H3 hyperacetylation in reci...

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Détails bibliographiques
Auteurs principaux: Li, Ziqiang, Luo, Zhonghui, Scharff, Matthew D.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC524454/
https://ncbi.nlm.nih.gov/pubmed/15486086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406827101
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