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H3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombination

Class switch recombination (CSR) involves a DNA rearrangement in the Ig heavy chain (IgH) gene that allows the same variable (V) region to be expressed with any one of the downstream constant region (C) genes to encode antibodies with many different effector functions. One hypothesis for how CSR is...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kuang, Fei Li, Luo, Zhonghui, Scharff, Matthew D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654022/
https://ncbi.nlm.nih.gov/pubmed/19276123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901368106
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