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H3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombination
Class switch recombination (CSR) involves a DNA rearrangement in the Ig heavy chain (IgH) gene that allows the same variable (V) region to be expressed with any one of the downstream constant region (C) genes to encode antibodies with many different effector functions. One hypothesis for how CSR is...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654022/ https://ncbi.nlm.nih.gov/pubmed/19276123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901368106 |
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