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H3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombination

Class switch recombination (CSR) involves a DNA rearrangement in the Ig heavy chain (IgH) gene that allows the same variable (V) region to be expressed with any one of the downstream constant region (C) genes to encode antibodies with many different effector functions. One hypothesis for how CSR is...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kuang, Fei Li, Luo, Zhonghui, Scharff, Matthew D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654022/
https://ncbi.nlm.nih.gov/pubmed/19276123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901368106
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