Uncoupling associations of risk alleles with endophenotypes and phenotypes: insights from the ApoB locus and heart‐related traits

Traditionally, genomewide association studies (GWAS) have emphasized the benefits of large samples in the analyses of age‐related traits rather than their specific properties. We adopted a realistic concept of genetic susceptibility to inherently heterogeneous, age‐related traits driven by the elusi...

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發表在:Aging Cell
Main Authors: Kulminski, Alexander M., Kernogitski, Yelena, Culminskaya, Irina, Loika, Yury, Arbeev, Konstantin G., Bagley, Olivia, Duan, Matt, Arbeeva, Liubov, Ukraintseva, Svetlana V., Wu, Deqing, Stallard, Eric, Yashin, Anatoliy I.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
主題:
Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242299/
https://ncbi.nlm.nih.gov/pubmed/27683205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12526
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