Uncoupling associations of risk alleles with endophenotypes and phenotypes: insights from the ApoB locus and heart‐related traits

Traditionally, genomewide association studies (GWAS) have emphasized the benefits of large samples in the analyses of age‐related traits rather than their specific properties. We adopted a realistic concept of genetic susceptibility to inherently heterogeneous, age‐related traits driven by the elusi...

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Opis bibliograficzny
Wydane w:Aging Cell
Główni autorzy: Kulminski, Alexander M., Kernogitski, Yelena, Culminskaya, Irina, Loika, Yury, Arbeev, Konstantin G., Bagley, Olivia, Duan, Matt, Arbeeva, Liubov, Ukraintseva, Svetlana V., Wu, Deqing, Stallard, Eric, Yashin, Anatoliy I.
Format: Artigo
Język:Inglês
Wydane: John Wiley and Sons Inc. 2016
Hasła przedmiotowe:
Original Articles
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242299/
https://ncbi.nlm.nih.gov/pubmed/27683205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12526
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