APOE region molecular signatures of Alzheimer’s disease across races/ethnicities

The role of even the strongest genetic risk factor for Alzheimer’s disease (AD), the APOE ε4 allele, in its etiology remains poorly understood. We examined molecular signatures of AD defined as differences in linkage disequilibrium patterns between AD-affected and unaffected Whites (2,673/16,246), H...

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Publicado en:Neurobiol Aging
Main Authors: Kulminski, Alexander M., Shu, Leonardo, Loika, Yury, Nazarian, Alireza, Arbeev, Konstantin, Ukraintseva, Svetlana, Yashin, Anatoliy, Culminskaya, Irina
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064423/
https://ncbi.nlm.nih.gov/pubmed/31813627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.11.007
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