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APOE region molecular signatures of Alzheimer’s disease across races/ethnicities

The role of even the strongest genetic risk factor for Alzheimer’s disease (AD), the APOE ε4 allele, in its etiology remains poorly understood. We examined molecular signatures of AD defined as differences in linkage disequilibrium patterns between AD-affected and unaffected Whites (2,673/16,246), H...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Kulminski, Alexander M., Shu, Leonardo, Loika, Yury, Nazarian, Alireza, Arbeev, Konstantin, Ukraintseva, Svetlana, Yashin, Anatoliy, Culminskaya, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064423/
https://ncbi.nlm.nih.gov/pubmed/31813627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.11.007
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