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APOE region molecular signatures of Alzheimer’s disease across races/ethnicities

The role of even the strongest genetic risk factor for Alzheimer’s disease (AD), the APOE ε4 allele, in its etiology remains poorly understood. We examined molecular signatures of AD defined as differences in linkage disequilibrium patterns between AD-affected and unaffected Whites (2,673/16,246), H...

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書誌詳細
出版年:Neurobiol Aging
主要な著者: Kulminski, Alexander M., Shu, Leonardo, Loika, Yury, Nazarian, Alireza, Arbeev, Konstantin, Ukraintseva, Svetlana, Yashin, Anatoliy, Culminskaya, Irina
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064423/
https://ncbi.nlm.nih.gov/pubmed/31813627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.11.007
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