Role of the Cys Loop and Transmembrane Domain in the Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors

Allosteric modulators of pentameric ligand-gated ion channels are thought to act on elements of the pathways that couple agonist binding to channel gating. Using α4β2 nicotinic acetylcholine receptors and the α4β2-selective positive modulators 17β-estradiol (βEST) and desformylflustrabromine (dFBr),...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Alcaino, Constanza, Musgaard, Maria, Minguez, Teresa, Mazzaferro, Simone, Faundez, Manuel, Iturriaga-Vasquez, Patricio, Biggin, Philip C., Bermudez, Isabel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2017
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241731/
https://ncbi.nlm.nih.gov/pubmed/27864368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.751206
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller