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Polymerase-Mediated Site-Specific Incorporation of a Synthetic Fluorescent Isomorphic G Surrogate into RNA
An enzyme-mediated approach for the assembly of singly modified RNA constructs in which specific G residues are replaced with (th)G, an emissive isomorphic G surrogate, is reported. Transcription in the presence of (th)G and native nucleoside triphosphates enforces initiation with the unnatural anal...
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| Yayımlandı: | Angew Chem Int Ed Engl |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5241218/ https://ncbi.nlm.nih.gov/pubmed/28000329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201609327 |
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