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Enzymatic Interconversion of Isomorphic Fluorescent Nucleosides: Adenosine Deaminase Transforms (th)A to (th)I, Two Distinct Fluorophores
Adenosine deaminase, a major enzyme involved in purine metabolism, converts an isomorphic fluorescent analogue of adenosine ((th)A) to an isomorphic inosine analogue ((th)I), which possesses distinct spectral features, allowing one to monitor the enzyme-catalyzed reaction and its inhibition in real...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947497/ https://ncbi.nlm.nih.gov/pubmed/24288262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201307064 |
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