लोड हो रहा है...
Cellular activity of siRNA oligonucleotides containing synthetic isomorphic nucleoside surrogates
Singly and multiply modified synthetic siRNA oligonucleotides, containing isomorphic surrogate nucleobases, show high interference potency in cell culture, suggesting the highly isomorphic RNA alphabet, based on a thieno[3,4-d]-pyrimidine core, is tolerated well by the cellular silencing machinery.
में बचाया:
| में प्रकाशित: | Chem Commun (Camb) |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4298453/ https://ncbi.nlm.nih.gov/pubmed/25500944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc08809c |
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