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Transforming growth factor β-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation
Transforming growth factor β (TGFβ) is one of few known negative regulators of hematopoiesis, yet the mechanisms by which it affects cell cycle arrest and stem cell quiescence are poorly understood. Induction of the cyclin-dependent kinase inhibitors, p15INK4b (p15) and p21WAF1 (p21) is important fo...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524079/ https://ncbi.nlm.nih.gov/pubmed/15477587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406771101 |
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