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E2F and Histone Deacetylase Mediate Transforming Growth Factor β Repression of cdc25A during Keratinocyte Cell Cycle Arrest

cdc25A is a tyrosine phosphatase that activates G(1) cyclin-dependent kinases (Cdk’s). In human keratinocytes, cdc25A expression is down-regulated after the initial drop in Cdk activity caused by cell exposure to the antimitogenic cytokine transforming growth factor β (TGF-β) or removal of serum fac...

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Bibliografische gegevens
Hoofdauteurs: Iavarone, Antonio, Massagué, Joan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC83949/
https://ncbi.nlm.nih.gov/pubmed/9858615
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