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NFX1 Interacts with mSin3A/Histone Deacetylase To Repress hTERT Transcription in Keratinocytes

Transcription of the catalytic subunit of telomerase (hTERT) in keratinocytes can be induced by human papillomavirus type 16 (HPV16) E6/E6AP ubiquitin ligase through degradation of the repressor, NFX1-91. Here, we demonstrate that NFX1-91 interacts with the corepressor complex mSin3A/histone deacety...

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Bibliografiske detaljer
Main Authors: Xu, Mei, Luo, Weifeng, Elzi, David J., Grandori, Carla, Galloway, Denise A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493374/
https://ncbi.nlm.nih.gov/pubmed/18505829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01969-07
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