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NFX1-123 Increases hTERT Expression and Telomerase Activity Posttranscriptionally in Human Papillomavirus Type 16 E6 Keratinocytes

High-risk human papillomavirus (HPV) E6 protein induces telomerase activity through transcriptional activation of hTERT, the catalytic subunit of telomerase. HPV type 16 (HPV16) E6 interacts with two splice variants of NFX1 to increase hTERT expression. NFX1-91 is a transcriptional repressor of hTER...

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Detalhes bibliográficos
Main Authors: Katzenellenbogen, Rachel A., Vliet-Gregg, Portia, Xu, Mei, Galloway, Denise A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698580/
https://ncbi.nlm.nih.gov/pubmed/19369336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02556-08
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