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Human Papillomavirus 16E6 and NFX1-123 Potentiate Notch Signaling and Differentiation without Activating Cellular Arrest

High-risk human papillomavirus (HR HPV) oncoproteins bind host cell proteins to dysregulate and uncouple apoptosis, senescence, differentiation, and growth. These pathways are important for both the viral life cycle and cancer development. HR HPV16 E6 (16E6) interacts with the cellular protein NFX1-...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Vliet-Gregg, Portia A., Hamilton, Jennifer R., Katzenellenbogen, Rachel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383269/
https://ncbi.nlm.nih.gov/pubmed/25723053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.02.002
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