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Serum-Induced Expression of the cdc25A Gene by Relief of E2F-Mediated Repression

The cdc25A gene encodes a tyrosine phosphatase which activates cyclin-dependent kinase activity in the G(1) phase of the cell cycle. cdc25A RNA levels are induced from 3 to 6 h after serum induction of serum-starved NIH 3T3 cells, suggesting that the cdc25A gene is a delayed-early gene. Analysis of...

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Détails bibliographiques
Auteurs principaux: Chen, Xi, Prywes, Ron
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC84267/
https://ncbi.nlm.nih.gov/pubmed/10373518
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