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CDC25A Phosphatase Is a Target of E2F and Is Required for Efficient E2F-Induced S Phase

Functional inactivation of the pRB pathway is a very frequent event in human cancer, resulting in deregulated activity of the E2F transcription factors. To understand the functional role of the E2Fs in cell proliferation, we have developed cell lines expressing E2F-1, E2F-2, and E2F-3 fused to the e...

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Main Authors: Vigo, Elena, Müller, Heiko, Prosperini, Elena, Hateboer, Guus, Cartwright, Peter, Moroni, Maria Cristina, Helin, Kristian
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 1999
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC84608/
https://ncbi.nlm.nih.gov/pubmed/10454584
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