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CDC25A Phosphatase Is a Target of E2F and Is Required for Efficient E2F-Induced S Phase

Functional inactivation of the pRB pathway is a very frequent event in human cancer, resulting in deregulated activity of the E2F transcription factors. To understand the functional role of the E2Fs in cell proliferation, we have developed cell lines expressing E2F-1, E2F-2, and E2F-3 fused to the e...

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Bibliografiska uppgifter
Huvudupphovsmän: Vigo, Elena, Müller, Heiko, Prosperini, Elena, Hateboer, Guus, Cartwright, Peter, Moroni, Maria Cristina, Helin, Kristian
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1999
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC84608/
https://ncbi.nlm.nih.gov/pubmed/10454584
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