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Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes.

Here we show that the lymphoid lineage-determining factors Ikaros and Aiolos can function as strong transcriptional repressors. This function is mediated through two repression domains and is dependent upon the promoter context and cell type. Repression by Ikaros proteins correlates with hypo-acetyl...

詳細記述

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書誌詳細
主要な著者: Koipally, J, Renold, A, Kim, J, Georgopoulos, K
フォーマット: Artigo
言語:Inglês
出版事項: 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171390/
https://ncbi.nlm.nih.gov/pubmed/10357820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.11.3090
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