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Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes.
Here we show that the lymphoid lineage-determining factors Ikaros and Aiolos can function as strong transcriptional repressors. This function is mediated through two repression domains and is dependent upon the promoter context and cell type. Repression by Ikaros proteins correlates with hypo-acetyl...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
1999
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171390/ https://ncbi.nlm.nih.gov/pubmed/10357820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.11.3090 |
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